The Callewaert Lab focusses on all aspects of translational genomics based on patient-driven research. We embark in gene identification studies and deep-phenotyping studies for rare diseases to develop disease management guidelines. We contribute to gene and variant curation consortia and work with national and international networks to improve clinical care. We aim to unravel disease mechanisms using cell-based, organoid and animal modeling systems to develop disease-specific therapies.
Together with patient organizations, international consortia and our collaborators we strive for a better future for those affected with a rare disease.