Lisa Hamerlinck

I am a PhD student jointly affiliated to the FunGen lab and CallewaertLab since December 2021. I focus on the non-coding DNA sequences that regulate the SATB2 gene and on the mechanisms that link disruption of these sequences to disease. For this purpose, I use iPSC derived models, enhancer assays, CRISPRi and chromatin conformation capture techniques. Once the regulatory landscape is established, this information will be used to determine the potential of cis-regulation therapy (CRT) in cell lines of patients with SATB2-associated syndrome. Hence, this project will lead to improved diagnostics and therapy for SATB2-associated syndrome.    I followed the permanent education course on human genetics offered by the Belgian Society of Human Genetics, in order to continuously expand my knowledge on genetics.  I love tennis and I enjoy playing boardgames with friends and colleagues. I have been awarded an FWO fellowship to work on these exciting projects.